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Most patients regain weight after discontinuing GLP-1 or dual-agonist peptides if they do not maintain the dietary and lifestyle changes that supported weight loss

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Furthermore, associations between GLO-1 and immunoregulatory markers as PD-L1, TMB, and MSI strongly support exploring combination therapies with immune checkpoint blockade to achieve enhanced synergistic effects

Lower placental glutathione peroxidase activity has been observed in women with SGA compared with controls (Reference Lewandowska, Sajdak and Lubiski12)