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Even after successful isolation and expansion, NPPCs exhibit restricted proliferative capacity and a limited potential for specific differentiation into functional NP-like cells

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As a serine protease, hepsin presents challenges for administration as an intact or activated protein due to its tendency to auto-activate, degrade, and its overall instability (Li et al

Therefore, if a significant amount of the vitamin B12 in your blood is inactive, a blood test may show that you have normal vitamin B12 levels, even though you have vitamin B12 deficiency because of insufficient "active" vitamin B12