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Cyanocobalamin has sometimes been proposed as the worst source because it must be converted to the two coenzymatic forms (methyl and adenosyl) before it can be used, but the reality is that the body can efficiently convert cyanocobalamin into methylcobalamin and adenosylcobalamin without any problems

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Moreover, there exists evidence linking elevated Hcy levels to an increased risk of MetS (Sreckovic et al., 2017)

More specifically, iron is involved in the formation and regulation of melanin through its role in tyrosinase activity the enzyme responsible for melanin synthesis

Excessive nitric oxide production represents another theoretical concern