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Expression analysis of a panel of COVID-19 related genes at endpoint Z (blood aliquots added with culture medium and B12 excipient but not incubated) ( Figure S2 ) in addition to revealing distinctive transcriptional signatures of moderate and severe forms of the disease, have also shed light on the effects of glucocorticoid therapy on circulating leukocytes

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Orbitrap Exploris 480 was used for MS analysis with specific settings for full-MS and MS/MS scans