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B12 Injections and Mental Health: Its important to understand, however, that for people with normal B12 levels, there is no strong scientific evidence that taking extra B12either in pill form or by injectionwill improve depression, anxiety, or mood disorders

But human evidence is extremely limited

So far, vitamin B12 is only likely to improve performance and raise energy levels if you have a vitamin B12 deficiency

Vitamin B12 is required for the metabolism of proteins and carbohydrates

Both are shown in animal models to be particularly adept at suppressing TNF-alpha, a cytokine that is heavily linked with inflammatory bowel disease [16, 17, 18]