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Renal effects: Rare cases of interstitial nephritis and capillary necrosis have been reported in patients treated with diclofenac

Author contributions AB: Conceptualization, Data curation, Formal Analysis, Investigation, Methodology, Writingoriginal draft, Writingreview and editing

M., Pacheco-Barrios, K., Carvalho, S., Leite, J., Simis, M., Brunelin, J., Nakamura-Palacios, E

Transcription factor activity changes: GHK-Cu modulates activity of key transcription factors including NF-B (inflammation master regulator), AP-1 (stress response), Nrf2 (antioxidant response element activator), p53 (cell cycle and apoptosis regulator)