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This also limits NADH production which aids in preventing the further genesis of O 2 /H 2 O 2 by either enzyme or the respiratory chain

Second, individual variability in susceptibility to heat stress-induced damage calls for the development of personalized intervention strategies based on biomarkers of OS, such as 8-hydroxy-2-deoxyguanosine (8-OHdG) and ROS levels

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Two structural modifications (C18 fatty acid chain enabling albumin binding, and a substitution at position 8 conferring DPP-4 resistance) extend its half-life to approximately 1 week, enabling once-weekly subcutaneous dosing

This is a finding that should be investigated, not ignored