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For example, colonization of germ-free mice with Bacteroides thetaiotaomicron (191) or Escherichia coli Nissle 1917 (EcN) (192) led to up-regulation of genes encoding for proteins such as small proline-rich protein-2 (sprr2a) and ZO-1 involved in improving cellular adhesion

Lipids 2012;47:66978

Testosterone levels are typically improved through therapies specifically designed for testosterone support

However, brand-name medications are currently available, and compounding is only allowed when the patient needs a customized dosage or formulation that is not commercially available