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Triglyceride alters lysosomal cholesteryl ester metabolism in cholesteryl-ester laden macrophage foam cells

no human validation Approach Published mouse regimen Pattern 5 mg/kg IP, ~3x/week Duration Several weeks Notes Animal only

ELISA plates are polystyrene or propylene-made 96- or 384-well microplates used in labs to analyze many biomolecules simultaneously

Additionally, activation of the aryl hydrocarbon receptor (AHR) signaling pathway has been implicated in the transcriptional and possibly epigenetic regulation of both CYP27B1 and CYP24A1 ( 3.2 Dysregulation of vitamin D metabolism in chronic kidney disease In the context of CKD, the regulatory network governing vitamin D metabolism becomes markedly disrupted