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[Updated Jul 25, 2021]

The Effects of Proton Pump Inhibitors in Acid Hypersecretion-Induced Vitamin B12 Deficiency: A Systematic Review (2022)

Key Takeaways for Providers Standard GLP-1 therapies are highly effective for appetite regulation but often fail to address metabolic adaptation, leading to weight loss plateaus

The majority of patients may well have suffered in silence

To identify the selective cargos of V-ATPase-dependent autophagy, we tagged different organellar proteins with GFP at the C-terminal end and performed GFP-processing assays: We found a clear increase in the vacuolar degradation of ribosomal proteins Rps6A and Rpl10, indicating the induction of ribophagy (Fig