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Global prevalence of irritable bowel syndrome according to Rome III or IV criteria: a systematic review and meta-analysis

A central conundrum in immunosenescence research lies in navigating the dual risks of therapeutic interventions: suppressing age-associated inflammation (inflammaging) may inadvertently exacerbate infection susceptibility or compromise basal immune homeostasis, whereas overactivating inflammatory pathways to restore immune function risks precipitates autoimmune pathologies or acute inflammatory sequelae

Materials and methods Search strategy A comprehensive literature search was performed in the database PubMed

However, our study did not directly assess mitochondrial function or ROS levels, and thus, this mechanism remains speculative

26,27 Once attached to the appropriate receptor, the viruses enter the cell via one of two primary mechanisms