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This finding has important safety implications, as elevated IGF-1 levels associated with full GH therapy raise concerns about increased cancer risk, particularly for individuals with pre-existing malignancies or strong family histories

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Not for human or animal consumption, injection, diagnosis, or therapeutic application

Due to the global opioid crisis, the judicious use of chronic opioids is advised and only after informed decision-making with the patients and with periodic follow-ups to assess efficacy, adverse side effects, compliance, and potential of abuse or misuse