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igf-1 lr3 safety side effects IGF-1: Miracle Hormone or Health Hazard? IGF-1/LR3 - PRAMAH / THE

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doi: 10.1016/j.tips.2013.01.001

10.1093/ajcn/67.6.1219 238 Uriu-AdamsJ

In a renal proximal tubule-specific Tsc1 gene-knockout mouse model, downregulated AMPK phosphorylation was observed in the enlarged kidneys, which also exhibited aberrant proliferation of proximal tubule cells, renal interstitial inflammation, and fibrosis