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Using two separate techniques, one study established ACSL4 as a significant predictor of ferroptosis susceptibility and discovered that ACSL4 was the enzyme in the ACSL enzyme family that was specifically connected to ferroptosis, independent of the other ACSL enzymes (22)

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Clinically, QLQX is used in addition to standard heart failure therapy (beta-blockers, RAAS inhibitors, diuretics, etc.), not as a standalone treatment