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In short, intestinal barrier damage is not only a disease of the intestine itself, but also a detection agent for functional changes in other organs

10.1038/s41598-022-11516-x Sci Rep 88 GeoffroyP

TB-500 is studied primarily for its cellular migration-promoting, stem cell-mobilising, actin-sequestering, and anti-apoptotic properties across wound healing, cardiac, CNS, and musculoskeletal models

However, the direct oxidation of Cys and, to a lesser extent, methionine residues with H 2 O 2 can give rise to reversible modifications, such as sulfenic acid or disulfides or as methionine sulfoxides, respectively, which can be reduced by cellular activities

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