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Intriguingly, the ratio of protein to carbohydrates determines the catabolic pathway of gut bacteria, various catabolic products can contribute to regulating the gut-brain axis or maintaining the hosts nitrogen balance (93)

PubMed Sikiric, P., Seiwerth, S., Rucman, R., Turkovic, B., Rokotov, D.S., Brcic, L., Sever, M., Klicek, R., Radic, B., Drmic, D., Ilic, S., & Kolenc, D

One review of the field stated that intranasal drug delivery has emerged as a reliable method to bypass the BBB and treat neurological diseases. Its not a done deal, though

It is generally administered either into a muscle (intramuscularly) or a vein (intravenously)

Pain Physician, 15 (3), ES177ES189