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Roles of Nicotinamide N-Methyltransferase in Obesity and Type 2 Diabetes

S-adenosyl methionine (SAMe), the active form of the amino acid methionine, is the major metabolite in multiple metabolic pathways on which neuronal homeostasis depends

By preserving muscle mass during weight loss, patients set themselves up for easier weight maintenance, better physical function, and improved metabolic health

While short-term research (4-8 weeks) has been extensively studied and often shows good tolerability, long-term safety data is more limited, and several theoretical concerns warrant careful consideration

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