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Since BAP1 shows aberrant cytosolic abundance in glioma and because the BAP1-related pathway inhibiting ferroptosis is located in the nucleus, the abnormal distribution of BAP1 in glioma cells, compared to that in other cancer cells, and the BAP1 regulatory pathway in the nucleus can be new research targets

Microglia programmed cell death in neurodegenerative diseases and CNS injury

Mice expressing Cre recombinase under the mouse Gfap promoter ( mGfap Cre mice) were stereotactically injected with adeno-associated virus (AAV) vectors encoding Gstm1 or non-silencing control shRNAmir into the mPFC as previously described (Figure 2A)

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Release of active peptidyl arginine deiminases by neutrophils can explain production of extracellular citrullinated autoantigens in rheumatoid arthritis synovial fluid