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Madecassoside inhibits acne-induced oxidative damage and inflammation & boosts skin hydration in an in-vitro model

& Schmoll, H

This reprogrammed pathway leads to the production of ATP mainly at substrate level and regeneration of reducing equivalents needed for cells growth, redox balance, and metabolic energy

Primary endpoints of safety, tolerability and dose finding were met, and secondary endpoints of pharmacokinetics, objective response rate, disease control rate, and progression free survival are explored