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Cells were then washed with PBS and incubated with 2% FBS medium at 34.5 C and 5% CO 2

Glia 59 , 11811189 (2011)

Tirzepatide (Mounjaro) is a dual agonist: it activates both GLP-1 and glucose-dependent insulinotropic peptide (GIP) receptors, engaging two complementary appetite and metabolic pathways simultaneously

Reference: Powers SK, Ji LL, Leeuwenburgh C

What to Expect in Month 1 Appetite changes: Noticeable suppression begins week 3-4 for most Mild nausea: 40% experience some nausea, usually mild Injection site reactions: Redness, itching, or mild pain at injection site (14% of patients) Fatigue: Some patients report low energy as body adjusts Bowel changes: Either constipation or looser stools as medication affects gut motility 4 Essential Strategies for Month 1 1