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Thus, high and sustained concentrations of ROS can cause damage to many cellular and extracellular constituents, including DNA, proteins and lipids [15]

AMPK Insulin Sensitivity [61] AMPK increases the transport of GLUT4 to the plasma membrane, raises glucose uptake, and lessens the accumulation of fats in the tissues, thereby enhancing the insulin sensitivity in the entire body

E3 ligase CHIP and Hsc70 regulate Kv1.5 protein expression and function in mammalian cells

Downregulation of GPX4 in the spinal cord could lead to the development of NP induced by CCI and SNI models, as well as inflammatory pain induced by CFA