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Further, another inflammatory pathway marker transcription factor, nuclear factor kappa B (NF-B) activity has been shown to be increased in the brains of AD patients (Hong, Mast cells are present adjacent to the neurons and glial cells in thalamus, hypothalamus, and leptomeninges and activate them by cell-to-cell contacts as well as by releasing inflammatory and neurotoxic mediators (Theoharides et al., 2013)

High levels can mask B12 deficiency

Probes/primers are typically used in the form of one or more substantially purified oligonucleotides

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