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As reported for isatuximab and daratumumab, mass spectrometry analyses and the use of specific IFE-reflex assays (i.e., isatuximab Hydrashift assay, DIRA assay) can overcome interference by these therapeutic antibodies and allow more accurate measurements of serum M-protein in MM patients [48, 53,54,55]

In most people, these effects likely balance out, but individuals with pre-existing blood sugar concerns should monitor their glucose levels more frequently during the initial weeks of combination use

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