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They preassemble membrane-constricted structures at specific ER contact points and recruit division-related proteins from the cytoplasm, thereby initiating mitochondrial constriction and division

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Later, the same group discovered that mice that lacked NFB in astrocytes had reduced Mn-induced glial activation and neuronal loss ( in vitro and in vivo , while LRRK2 deletion in microglia reduced cytokine release in vitro (Kim et al., 2019)