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Concurrently, real-time clinical adjustment strategies are emerging, combining organoid-informed predictions with longitudinal monitoring toolssuch as tDNA for tracking metabolic mutation burden, and FDG-PET imaging to assess glucose metabolism [75]

[331,489] found L-kynurenine and KYNA among the metabolites most raised in terms of predicting both the severity of the disease and poor outcome (implying activation upstream of L-kynurenine as well as of KAT enzymes or transporters)

Nethravathy, V., Athhar, A., and Mosok, U.G., Asian J

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