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SCFA have been shown to have anti-inflammatory effects [225], epigenetic modulation capabilities and affect hormone secretion via G-protein coupled receptor binding [16]

doi: 10.3390/nu5030700 106 HawkesWCRichterBDAlkanZSouzaECDerricoteMMackeyBEet al

Box 616, 6200 MD Maastricht, Netherlands e-mail: [email protected] This article was submitted to Experimental Pharmacology and Drug Discovery, a section of the journal Frontiers in Pharmacology

Tekkok et al., 2005) and oligodendrocytes (Rinholm et al., 2011

To mimic progressive RRMS in patients, we have set up a relapsing-remitting EAE in Biozzi ABH mice, which also allows therapeutic intervention