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Osteoarthritis (rabbit model) Experimental Design: Animal: New Zealand white rabbit, collagenase induced knee osteoarthritis model

Lys-84, Asp-284, and Tyr-255 in IdeS and gasMac-1 have been shown to be important for maintaining the architecture of the active site, as mutation of these residues resulted in considerably decreased enzymatic activity (Agniswamy et al, 2006

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This category includes wintertime tiredness, which can sometimes be accompanied by blue moods and feelings of anxiety

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