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It can directly bind to its promoter region and induce its expression under stress conditions such as cholestasis, highlighting AhRs vital role in maintaining bile acid homeostasis (Xu et al., 2010

doi: 10.3389/fnagi.2024.1487875 Received 28 August 2024 Accepted 19 November 2024 Published 05 December 2024 Volume 16 - 2024 Edited by Enzo Emanuele, 2E Science, Italy Reviewed by Xiaoxiao Lin, University of California, Santa Barbara, United States David Toloza-Ramirez, Andres Bello University, Chile Updates Copyright 2024 Zhang, Zhang, Zhang, Tao and Zhang