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The TET enzyme family consists of three members: TET1, TET2, and TET3

75 Beyond supporting GSH levels and functions, NAC also directly scavenges ROS and enhances the antioxidant enzymes such as GPx and catalase (CAT)

Organ harvesting Mice were euthanised by cervical dislocation and tissues were flash-frozen in liquid nitrogen

Furthermore, disease-related phenotypes were not observed in transgenic mice expressing human SOD1 that has multiple mutations including those at copper and zinc binding sites (H46R/H48Q/H63G/H71R/H80R/H120G) and two free Cys residues (C6G/C111S) with an ALS-linked mutation, H43R, and co-expression of wild-type human SOD1 did not cause the disease [35]

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