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The in vitro experiments have confirmed that vitamin D could inhibit the growth of Mtb and secretion of pro-inflammatory cytokines in peripheral blood monocytes (Martineau et al., 2007), stimulate the receptor-induced expression of antimicrobial peptides, and up-regulate LL37 gene to induce the autophagy-related proteins Atg5 and Beclin-1 to mediate the killing effect (Periyasamy et al., 2020)

legal status and clinical fit still require review Research products and peptides require careful review of source quality, legality, and supervision

Lifestyle Modifications for Oxidative Stress Reduction Exercise with Caution: Engage in moderate-intensity physical activities like walking, cycling, or yoga to increase glutathione levels over time and reduce oxidative stress

ABCG2 contributes to the development of gout and hyperuricemia in a genome-wide association study

Summary Keywords microbiome-based interventions, probiotics, prebiotics, synbiotics, postbiotics, next-generation probiotics, microbiota-gut-brain axis (MGBA), neurodegenerative diseases (NDDs) Citation Auclair-Ouellet N, Kassem O, Bronner S, Oula M-L and Binda S (2025) Leveraging microbiome-based interventions to improve the management of neurodegenerative diseases: evidence for effects along the microbiota-gut-brain axis