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The therapeutic mechanism includes the reactivation of hormonal signaling pathways, demonstrated by significantly elevated plasma E2 levels in treated mice over time

& Avery, M

10.1016/j.cell.2012.03.042 Cell 17 DollS.FreitasF

In a 12-week study involving 120 patients with obesity and Type 2 diabetes at Yancheng First Peoples Hospital in China, researchers compared semaglutide alone with semaglutide plus dorzagliatin