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1 Introduction In 2024, the International Agency for Research on Cancer (IARC) released the latest GLOBOCAN 2022 database, which encompasses data on the incidence and mortality of 36 types of cancer across 185 countries or regions worldwide

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Neither approach shows a meaningful difference in outcomes

[3] [5] Topical application also keeps the copper load overwhelmingly local: intact stratum corneum is a substantial barrier to a ~403 Da charged metal complex, which limits systemic copper exposure the same barrier property that limits topical efficacy is what limits topical copper risk