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Blokhina et al., 2003)

Blood 111(7):3742-3750, 2008

The TRX antioxidant system is comprised of both TRX and thioredoxin reductase (27, 48, 175, 418)

however, p53 3RK failed to induce cell cycle arrest, senescence, or modulation and inhibited xCT expression, ultimately promoting the response to stress induced by ROS (68)