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In the rat aorta, HgCl 2 was shown to cause oxidative stress via NAPDH oxidation, resulting in decreased NO production, leading to endothelial dysfunction, and enhanced vascular reactivity following phenylephrine exposure (a drug used for vasoconstriction) (Cordeiro et al

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Third (3) the average binding energy calculation (ABEC)

Figure 3 Biological mechanisms affected by time on ART in PrEP and PWH To assess the biological mechanisms affected by time on ART we performed a GESECA analysis separately for the PrEP and PWH groups ( Supplementary Table S3 )

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