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The results revealed that S32A mutation in RIPK1 significantly increased the sensitivity of MEFs to death induced by TNF alone and resulted in RIPK1 kinase activation, which can be blocked by RIPK1 kinase inhibitor Nec-1s (Fig

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Pairing weight loss therapy with resistance training significantly reduces lean mass loss

Ongoing efforts should emphasize longitudinal data, multiomic integration, sex-specific trajectories, and cross-disciplinary collaboration to further the clinical applicability and translational potential of computational E/I balance modeling in autism research