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In univariate analysis SHUNT% was the strongest single predictor of new clinical decompensation, liver-related death, or liver transplantation (n=13 with clinical outcomes, AUROC 0.886 for V1.1, 0.853 for V2.0, and 0.834 for LDT 1.0) with no significant differences in operating characteristics between Test versions

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Therapeutic intervention in experimental allergic encephalomyelitis by administration of uric acid precursors

investigated the role of the cytochrome P450 enzyme CYP1B1 in Mn-induced toxicity using in vitro experiments with human cerebral microvascular endothelial cells (hCMEC/D3), an in vitro model of the BBB [141]