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PLoS ONE 5:e11335 Cooper CE, Patel RP, Brookes PS, Darley-Usmar VM (2002) Nanotransducers in cellular redox signaling: modification of thiols by reactive oxygen and nitrogen species

As an exogenous source of antioxidants, the diet plays a significant role in protecting against oxidative stress

ChisI-CMicuC-MToaderAMoldovanRLeleLClichiciSet al

J Clin Invest 120(9):33773388

These findings suggest that MSG may increase cellular oxidative stress by suppressing the antioxidant defense system, and TA may significantly alleviate these adverse effects both at the gene level and in terms of enzyme activity, thus renormalizing the cellular redox level