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Symptoms of B12 deficiency include: Fatigue Low mood or personality/mood changes Irritability Lethargy Headaches Palpitations Loss of appetite Pale yellow tint to the skin A feeling of pins and needles (paraesthesia) Poor memory Impaired cognitive performance Depression Weakness Impaired digestion Inflammation Gastrointestinal lesions Neurological damage Since B12 is primarily found in animal products, any change in ones diet that leads to a decrease in the consumption of such products such as a vegan , vegetarian, or low-fat diet can increase the chance of a person developing a B12 deficiency

It represents a new class of weight-loss medications and has a unique mechanism of action

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By delivering methylcobalamin or cyanocobalamin directly into muscle tissue, the vitamin enters your bloodstream immediately at nearly 100% bioavailability

These findings suggest potential applications in tissue engineering research