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However, a long waveguide diminishes the fringe contrast (\(v\)) of the waveguide interferometer due to increased transmission loss, and thus reduces the efficiency of phase-to-intensity conversion and the overall PTS signal

These side effects can often be managed by taking the medication with food, taking a drug holiday, switching to an extended-release formulation, or starting with a low dosage and gradually increasing over time (Wexler 2021b)

FIGURE 4 4 Crosstalk between mitochondrial dynamics, biogenesis, and mitophagy MQC is a dynamic and coordinated process in which mitochondrial biogenesis, mitophagy, and mitochondrial fission/fusion interact and regulate each other to maintain mitochondrial homeostasis

If yes, no specific follow up for B 12 is required

The 6-week intervention demonstrated significantly greater efficacy compared to longer durations (6 weeks), which showed diminished effects