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To elucidate the islet inflammation (insulitis), we analyzed hematoxylin and eosin (H&E)-stained pancreatic sections from 8 weeks of age Xbp1 fl/fl and Xbp1 -/- mice and showed that knockout mice had markedly reduced islet infiltration by immune cells (Fig

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Recent studies suggest that novel drugs such as Ferrostatin-1 and Liproxstatin-1, by modulating iron-dependent cell death pathways, exert protective effects against ischemic stroke