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For instance, short-chain fatty acids (SCFAs) produced by gut bacteria have been shown to have neuroprotective effects and promote BDNF expression (Church et al

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Our early studies demonstrated that vascular dysfunction of epineural arterioles that provide circulation to the sciatic nerve preceded slowing of nerve conduction velocity in streptozotocin-induced diabetes (92, 93)

doi: 10.1126/science.107.2784.476