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Colorectal cancer: copper homeostasis disruption Recent work suggests ESC may exploit copper dysregulation in colorectal cancer (CRC), complementing its known pro-apoptotic and anti-EMT actions

73 Redox signaling involves reversible oxidationreduction of cysteinyl residues of proteins in cell membranes or within cells in response to the redox potential of the extracellular cysteine/cystine (CyS/Cys-S-S-Cys) pool

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Therefore, the notable efficacy of nAbs in established Ebola virus infection in monkeys and humans, even when symptoms are present, is perhaps a surprise, albeit an encouraging one for nAb therapies, given the severity and rapid spread of Ebola virus infection in vivo 157,158,159