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HZ: Methodology, Project administration, Writing original draft

Treating irAEs without compromising cancer treatment response One important challenge with treating irAEs is ensuring that the approaches do not interfere with antitumor responses

McCully, 1983, 1996

developing such guidance would be a valuable step toward standardizing care

Acknowledgements We thank members of the Cryo-electron Microscopy and Tomography Center of St Jude Childrens Research Hospital for help with cryo-EM data collection