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PFD (standard treatment and VCN were able to alleviate the damaging effects produced by BLM with varying degrees, where lung sections of VCN-treated animals showed better histological observations compared to PFD, which was observed in the alveolitis score as well

Future therapeutic breakthroughs will likely depend on integrated strategies that simultaneously tackle multiple barriers: improved delivery systems to ensure broad, sustained target engagement

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subsequently, through gene function enrichment analysis (such as Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis), clarifying the regulatory roles of target genes in biological processes, molecular functions and signaling pathways

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