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In fact, platelet-activating factor binding to PAFr leads to the production of inositol trisphosphate (IP3) through the phosphatidylinositol cycle, which in turn binds to inositol 1,4,5-triphosphate receptor type 1 (IP3R1) to induce the release of Ca 2+ stored in the endoplasmic reticulum (Kroegel et al., 1989

Numbers were small but there were fewer viraemias with CMV, EBV, Adenovirus and HHV6 compared to 42 historical patients who did not receive an add-back

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