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The vast majority of myelofibrosis patients eventually develop anemia, causing them to discontinue treatments and require transfusions, said Nina Mojas, senior vice president of oncology global product strategy at GSK in the same press release

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Since metformin improves insulin sensitivity and steatosis in MASLD 58 , these findings support a protective role of GADD45 in limiting inflammation, fibrosis, and progression to MASH

IV therapy may not be appropriate for people with certain medical conditions (for example, some heart, kidney, or fluid-balance concerns) or for those who are unwell in a way that requires medical assessment