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Bile acid glucuronides are substrates for the multidrug resistance-associated protein 3 (MRP3/ABCC3), an efflux transporter located on the basolateral membrane of hepatocytes that transports bile acid glucuronides out of the liver for urinary excretion, e.g., bile acid detoxification

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Formation of an :2 hemicomplex at the CTD of AAGAB Next, we sought to determine the molecular mechanism by which the bi-handed chaperone AAGAB regulates AP2 assembly