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Ischemic Cell Damage, fibrosis Fibrosis Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury

It catalyzes the esterification of long-chain polyunsaturated fatty acids (PUFAs, (e.g., arachidonic acid) into membrane phospholipids, making them substrates for peroxidation by enzymes like lipoxygenases (ALOXs) ( 2+ , is an essential catalyst for ferroptosis via the Fenton reaction

They found that BHB inhibits HDAC3 binding to the Claudin-5 promoter under high glucose (HG) conditions

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It's a serious concern, Dizon says