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Antiinflammatory Therapies in Myocardial Infarction: Failures, Hopes and Challenges

New insights into nitric oxide metabolism and regulatory functions

Adapted from [22] In 1957, Freeman and Hafkesbring compared the plasma and gastric fluid ascorbic acid concentrations (which were known to reliably represent the total body stores of ascorbic acid) of 108 patients with gastric disease and 113 controls [23]

GSH is not just a good biological antioxidant because of its reaction rate with HOCl which is generated during inflammations by myeloperoxidase but rather because the higher oxidation products generated are effective antioxidants