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Studies of global IGF-I KO mice (50,51), which survive to adulthood, show decreased bone formation rates, but higher trabecular bone mass (BV/TV), indicating reduction in both osteogenic and osteoclastogenic activities in the bones

It has been studied for its ability to stimulate endogenous growth hormone production, which plays a role in metabolism, cellular repair, and various endocrine functions

These signaling molecules activate biological pathways, which cells have used to respond to trauma, injury, and surgical metabolic stress

Now they have no idea whats working, whats causing any side effect, and theyve made it impossible to learn anything useful about their own body

Contraindicated in cardiovascular disease and with nitrate use